PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Water extract of red berries exerted antidepressive-like effects and in vivo antioxidant activity [PMID:29353203]
Water extract significantly inhibited cell proliferation and induced caspase-dependent apoptosis in HCT15 and CO115 cell lines [PMID:22596086]
Ethanol:water extract inhibited growth of breast, lung, cervical, and hepatocellular human carcinoma cell lines [PMID:28460934]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 29353203 (2018) — The water extract of tutsan (Hypericum androsaemum L.) red berries exerts antidepressive-like effects and in vivo antioxidant activity in a mouse model of post-stroke depression. · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
- 2.PMID: 26973675 (2016) — Polar Constituents and Biological Activity of the Berry-Like Fruits from Hypericum androsaemum L. · Frontiers in plant science
- 3.PMID: 27864112 (2017) — Polar extracts from the berry-like fruits of Hypericum androsaemum L. as a promising ingredient in skin care formulations. · Journal of ethnopharmacology
- 4.PMID: 15325741 (2004) — Hypericum androsaemum infusion increases tert-butyl hydroperoxide-induced mice hepatotoxicity in vivo. · Journal of ethnopharmacology
- 5.PMID: 34849072