PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 15 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Extract suppressed growth of HT-29 cancer cells in a dose- and time-dependent manner and increased apoptosis 2-fold [PMID:23069328].
Polyphenols inhibited cell viability and induced apoptosis via caspase-3 induction [PMID:21391128].
Evidence summary
PubMed sources
- 1.PMID: 23069328 (2013) — The Australian fruit Illawarra plum (Podocarpus elatus Endl., Podocarpaceae) inhibits telomerase, increases histone deacetylase activity and decreases proliferation of colon cancer cells. · The British journal of nutrition
- 2.PMID: 21875324 (2011) — Potential antioxidant, antiinflammatory, and proapoptotic anticancer activities of Kakadu plum and Illawarra plum polyphenolic fractions. · Nutrition and cancer
- 3.PMID: 36365337 (2022) — Bioassay Guided Fractionation Protocol for Determining Novel Active Compounds in Selected Australian Flora. · Plants (Basel, Switzerland)
- 4.PMID: 40916307 (2025) — A Scoping Review of Chemical, Pharmacological and Toxicological Properties and Clinical Applications of Australian Indigenous Medicine. · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
- 5.PMID: 39063267