PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 26 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Leaf extracts significantly reduced parasitemia and protected the spleen, liver, and lungs from tissue injury and oxidative stress [PMID:26109255, 29630927, 40917784].
Leaf extract mitigated lead-acetate-induced damage and apoptosis in the kidneys, brain, liver, and testes [PMID:27330278, 28123424, 27391413, 27052307].
Leaf extract decreased parasitemia by 70%, reduced weight loss, and mitigated spleen and liver injury [PMID:30898472, 32346351].
Leaf extracts and isolated peptides showed antimicrobial activity against various Gram-positive and Gram-negative bacteria and yeasts such as Candida albicans [PMID:32210676, 11167035, 10363845].
Treatment significantly increased antioxidant status and reduced serum marker enzymes (ALT, AST, ALP, LDH) [PMID:16117622].
Evidence summary
PubMed sources
- 1.PMID: 29062263 (2017) — Indigofera oblongifolia leaf extract regulates spleen macrophage response during Plasmodium chabaudi infection. · Saudi journal of biological sciences
- 2.PMID: 32210676 (2020) — Anthelmintic and antimicrobial activity of Indigofera oblongifolia leaf extracts. · Saudi journal of biological sciences
- 3.PMID: 27330278 (2016) — Indigofera oblongifolia mitigates lead-acetate-induced kidney damage and apoptosis in a rat model. · Drug design, development and therapy
- 4.PMID: 40917784 (2025) — Morphometric analysis and immunobiological investigation of Indigofera oblongifolia on the infected lung with Plasmodium chabaudi. · Open life sciences
- 5.PMID: 28123424 (2016)