PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Aqueous extract almost entirely eliminated preestablished cholesterol gallstones in mice and promoted bile secretion [PMID:25794804].
Aqueous extract and rutin reduced renal calcium oxalate deposition and renal tissue injury in rat and mouse models [PMID:40692330, 40063111, 42193124].
Polysaccharides reduced cholesterol and triglyceride levels in high-fat diet mice via gut microbiota modulation [PMID:37419267].
Aqueous extract elicited dose-dependent hypouricemic effects in oxonate-induced hyperuricemic mice [PMID:12776538].
Ethanolic extract and quercetin significantly reduced serum ALT and AST activities in mice [PMID:22621991].
Safety & adverse effects
Drug interactions
Evidence summary
PubMed sources
- 1.PMID: 37419267 (2023) — Lysimachia christinae polysaccharide attenuates diet-induced hyperlipidemia via modulating gut microbes-mediated FXR-FGF15 signaling pathway. · International journal of biological macromolecules
- 2.PMID: 18335347 (2008) — Triterpene saponins from Lysimachia christinae. · Journal of Asian natural products research
- 3.PMID: 31055581 (2019) — The Effects of Lysimachia christinae Hance Extract Fractions on Endothelium-Dependent Vasodilatation. · Pharmacology
- 4.PMID: 25794804 (2015) — Lysimachia christinae Hance regresses preestablished cholesterol gallstone in mice. · Journal of ethnopharmacology
- 5.PMID: 29636055 (2018) — Evaluation of the antioxidant and endothelial protective effects of Lysimachia christinae Hance (Jin Qian Cao) extract fractions.