PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 5 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Pulsed electric field-extracted polysaccharide (KEP) controlled the continuous increase of fasting blood glucose levels in streptozotocin-induced diabetic mice [PMID:36570142].
The amide derivative 4l of anticopalic acid exhibited cytotoxic activity against MDA-MB-231 triple-negative breast cancer cells (IC50 of 13.73 µM) and leukemia cell lines HL-60 and MOLT-3 [PMID:37596365].
Abieta-8,11,13-trien-11-ol isolated from rhizomes was found to be a potent aromatase inhibitor with an IC50 value of 3.7 µM [PMID:34110821].
Evidence summary
PubMed sources
- 1.PMID: 37596365 (2023) — The amide derivative of anticopalic acid induces non-apoptotic cell death in triple-negative breast cancer cells by inhibiting FAK activation. · Scientific reports
- 2.PMID: 30556802 (2019) — Jiangella endophytica sp. nov., an endophytic actinomycete isolated from the rhizome of Kaempferia elegans. · International journal of systematic and evolutionary microbiology
- 3.PMID: 30699955 (2019) — Complete Chloroplast Genome Sequences of Kaempferia Galanga and Kaempferia Elegans: Molecular Structures and Comparative Analysis. · Molecules (Basel, Switzerland)
- 4.PMID: 34110821 (2021) — Diterpenoids with Aromatase Inhibitory Activity from the Rhizomes of Kaempferia elegans. · Journal of natural products
- 5.PMID: 36570142