PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
A single 300 mg dose of whole plant powder significantly improved pulmonary function parameters (FVC, FEV1, PEFR, FEF25-75%), though the effect was less than standard bronchodilators [PMID: 10433479].
Kantakari Avaleha and its granule form were evaluated for efficacy in managing mild to moderate bronchial asthma [PMID: 38075186].
Fruit extract decreased hyperoxaluria, calcium, and uric acid, improved renal function, and produced antioxidant effects [PMID: 23112535].
Methanol leaf extracts (200 mg/kg bw) acted as efficient antihyperglycemic agents with potent antioxidant activity [PMID: 22014732].
Ethanolic stem extract showed anti-psoriatic potential in Imiquimod-induced mice [PMID: 28052238] and in human HaCaT keratinocytes [PMID: 39032661].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 29568195 (2018) — Evaluation of Antithrombotic Activities of Solanum xanthocarpum and Tinospora cordifolia. · Pharmacognosy research
- 2.PMID: 37110723 (2023) — Bioprospective Role of Ocimum sanctum and Solanum xanthocarpum against Emerging Pathogen: Mycobacterium avium Subspecies paratuberculosis: A Review. · Molecules (Basel, Switzerland)
- 3.PMID: 23112535 (2012) — Antiurolithiatic Effects of Solanum xanthocarpum Fruit Extract on Ethylene-Glycol-Induced Nephrolithiasis in Rats. · Journal of young pharmacists : JYP
- 4.PMID: 39032661 (2024) — Anti-psoriatic potential of medicinal plants, Alstonia scholaris, Wrightia tinctoria, and Solanum xanthocarpum, using human HaCaT keratinocytes by multi-parametric analysis. · Journal of ethnopharmacology
- 5.PMID: 10433479