PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
A randomized controlled dietary intervention showed differential abundances of nine postprandial miRNAs in healthy volunteers [PMID:39619950].
Review indicates that kawakawa contains natural products with documented potential effects on glucose metabolism, contributing to putative anti-diabetic effects [PMID:32694996].
A pilot randomized crossover study (TOAST) investigated whether kawakawa tea can modulate postprandial glucose metabolism in healthy volunteers [PMID:35458200].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 38389156 (2024) — Human Metabolism and Excretion of Kawakawa (Piper excelsum) Leaf Chemicals. · Molecular nutrition & food research
- 2.PMID: 30572092 (2019) — Composition and safety evaluation of tea from New Zealand kawakawa (Piper excelsum). · Journal of ethnopharmacology
- 3.PMID: 39619950 (2024) — Anti-inflammatory effects of kawakawa (Piper excelsum): An integrative mRNA-miRNA approach. · Food science & nutrition
- 4.PMID: 35458200 (2022) — Acute Effects of Kawakawa (Piper excelsum) Intake on Postprandial Glycemic and Insulinaemic Response in a Healthy Population. · Nutrients
- 5.PMID: 32694996 (2020) — The Potential of Anti-Diabetic Rākau Rongoā (Māori Herbal Medicine) to Treat Type 2 Diabetes Mellitus (T2DM) Mate Huka: A Review.