PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 9 PubMed articles · model: gemma4:31b
Summary
Background
Active compounds
Mechanism of action
Clinical evidence
DLBS3233 (combined bioactive fraction of C. burmanii and L. speciosa) improved insulin resistance better than placebo, as evidenced by a reduced HOMA-IR (-27.04% vs -4.90%) [PMID:27099473].
DLBS3233 was evaluated as an add-on therapy for patients inadequately controlled by metformin and other oral antidiabetic agents to reduce HbA1c levels [PMID:27451997].
DLBS3233 was studied for its metabolic and reproductive efficacy and safety in insulin-resistant women with PCOS, comparing its effect on HOMA-IR against metformin-XR [PMID:39033369].
Ethanol extract of C. burmanii demonstrated antibiofilm effectiveness against Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans in vitro [PMID:35436792].
Cinnamon extract showed potential as anti-insomnia medication in rats by decreasing the adrenal coefficient and related hormones [PMID:36317999].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 35436792 (2022) — Antimicrobial and Antibiofilm Activity of Cinnamon (Cinnamomum burmanii) Extract on Periodontal Pathogens-An in vitro study. · European journal of dentistry
- 2.PMID: 36317999 (2022) — The Potential of Cinnamon Extract (Cinnamomum burmanii) as Anti-insomnia Medication through Hypothalamus Pituitary Adrenal Axis Improvement in Rats. · Acta medica academica
- 3.PMID: 27099473 (2016) — Insulin sensitizer in prediabetes: a clinical study with DLBS3233, a combined bioactive fraction of Cinnamomum burmanii and Lagerstroemia speciosa. · Drug design, development and therapy
- 4.PMID: 39033369 (2024) — The Efficacy and Safety of DLBS3233, A Combined Bioactive Fraction of Cinnamomum burmanii and Lagerstroemia speciosa Plants on The Endocrine-Metabolic Profile of Women with Polycystic Ovary Syndrome: A Randomized Clinical Trial. · International journal of fertility & sterility
- 5.PMID: 22043982