PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Active compounds
Mechanism of action
Clinical evidence
Topical and oral extracts of Pinus koraiensis needles (PKN) attenuated clinical symptoms, including hemorrhage and erythema, by regulating immunity and suppressing inflammation in mice and HaCaT cells [PMID:35301731].
Leaf extract (PKL) demonstrated anti-fatigue potential in mice by decreasing plasma lactate, LDH, and BUN, while increasing superoxide dismutase and glutathione peroxidase [PMID:36076511].
Pine nut peptide-zinc chelate improved learning and memory, stopped brain aging, and controlled gut flora by ameliorating AChE and ChAT levels [PMID:37821052].
Essential oil from needles (PKEO) inhibited the growth, biofilm formation, and glucose metabolite acidogenicity of methicillin-resistant Staphylococcus aureus [PMID:38202618].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 37652269 (2023) — Neurotrophic neolignans of Pinus koraiensis twigs. · Fitoterapia
- 2.PMID: 36726668 (2022) — Genetic diversity analysis and fingerprint construction of Korean pine (Pinus koraiensis) clonal seed orchard. · Frontiers in plant science
- 3.PMID: 37821052 (2023) — Ameliorative effects of pine nut peptide-zinc chelate (Korean pine) on a mouse model of Alzheimer's disease. · Experimental gerontology
- 4.PMID: 37952447 (2023) — Water-extractable polysaccharide fraction PNE-P1 from Pinus koraiensis pine nut: Structural features and immunostimulatory activity. · Carbohydrate research
- 5.PMID: 35301731 (2022) — Pinus koraiensis needle or cone extracts alleviate atopic dermatitis symptoms by regulating immunity and suppressing inflammation in HaCaT cells and Nc/Nga mice.