PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
A mixture of Hwangchil and unripe Bokbunja extract (HDR-2) was studied for safety and effectiveness on blood pressure [PMID:33739883]
An extract of R. coreanus Miq. and A. membranaceus Bunge was investigated for improving the Kupperman index (KI) score [PMID:35251207]
Water-soluble extract (MN705) prevented kidney fibrosis in mouse models via TGF-β/Smad pathway inhibition [PMID:40354602]
Unripe extract (RCE) blocked PD-1/PD-L1 interaction and, when combined with oxaliplatin, reduced tumor growth in humanized PD-1 mice [PMID:33147777, 36139451]
Water extract (BRWE) inhibited lipid accumulation in human mesenchymal stem cells and promoted browning of white adipose tissue in mice [PMID:31509935]
Evidence summary
PubMed sources
- 1.PMID: 40354602 (2025) — Rubus coreanus extract prevents kidney fibrosis through TGF-β/Smad pathway inhibition. · PloS one
- 2.PMID: 33147777 (2020) — Unripe Black Raspberry (Rubus coreanus Miquel) Extract and Its Constitute, Ellagic Acid Induces T Cell Activation and Antitumor Immunity by Blocking PD-1/PD-L1 Interaction. · Foods (Basel, Switzerland)
- 3.PMID: 25045891 (2014) — Mistaken identity: clarification of Rubus coreanus Miquel (Bokbunja). · Molecules (Basel, Switzerland)
- 4.PMID: 31509935 (2019) — Black Raspberry (Rubus coreanus Miquel) Promotes Browning of Preadipocytes and Inguinal White Adipose Tissue in Cold-Induced Mice. · Nutrients
- 5.PMID: 22924523 (2012)