PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 18 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Krameria lappacea root extract (KLRE) exhibited notable anticoccidial activity, including oocyst suppression and protection of the jejunum, although it did not reach the efficacy level of amprolium [PMID:38407507, PMID:38751432, PMID:40313946, PMID:39055709]
Root extracts show antibacterial activity against Gram-positive and Gram-negative bacteria, specifically inhibiting the growth, biofilm formation, adhesion, and invasion of Methicillin-Resistant Staphylococcus aureus (MRSA) [PMID:41306278, PMID:33924336]
Dichloromethane extracts and isolated lignan derivatives exhibited topical antiedematous properties comparable to indomethacin in a mouse ear model [PMID:21800856]
Petroleum ether extracts demonstrated cytotoxic potential against the human breast cancer cell line MCF-7 [PMID:33981173, PMID:41306278]
Evidence summary
PubMed sources
- 1.PMID: 38407507 (2024) — Anticoccidial and jejunum-protective effects of Krameria lappacea roots extract on experimental Eimeria papillata infection. · Microscopy research and technique
- 2.PMID: 2813572 (1989) — Proanthocyanidins from Krameria triandra root. · Planta medica
- 3.PMID: 38751432 (2024) — Krameria lappacea root extract's anticoccidial properties and coordinated control of CD4 T cells for IL-10 production and antioxidant monitoring. · Frontiers in immunology
- 4.PMID: 41306278 (2025) — Antibacterial activity of Krameria lappacea root extract against gram-positive and gram-negative bacteria and its cytotoxicity on lung and breast cancer cell lines. · Frontiers in microbiology
- 5.PMID: 33981173 (2021)