PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 11 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Trilobolide and its acetoxy analog are strong activators of cytokine secretion [PMID:23747321].
Rhizome and fruit essential oils show significant antimicrobial effects against Escherichia coli, Klebsiella pneumoniae, and Candida albicans [PMID:30549907].
Addition of 2.0% Laser trilobum spice significantly inhibited the growth of natural microflora (total viables, coliforms, psychrotrophs, and yeasts-moulds) in ground meat [PMID:2052071].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 27600788 (2017) — Immunoassay for determination of trilobolide. · Steroids
- 2.PMID: 33291419 (2020) — Large Scale Conversion of Trilobolide into the Payload of Mipsagargin: 8-O-(12-Aminododecanoyl)-8-O-Debutanoylthapsigargin. · Biomolecules
- 3.PMID: 23747321 (2013) — Trilobolide and related sesquiterpene lactones from Laser trilobum possessing immunobiological properties. · Fitoterapia
- 4.PMID: 30549907 (2017) — Composition and Antimicrobial Properties of Essential Oils of Laser trilobum Rhizomes and Fruits. · Natural product communications
- 5.PMID: 2052071 (1991) — Effect of Laser trilobum spice on natural microflora of köfte, a Turkish ground meat product.