PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Demonstrated peripheral antinociceptive properties (inhibiting acetic-acid-induced writhing), central analgesic effects at the spinal level (tail flick assay), and supraspinal efficacy (hot plate assay) in animal models [PMID:38731572].
Alkaloid-rich bark extract and laurolitsine reduced fasting glucose, HbA1c, and GSP, while improving insulin sensitivity and oral glucose tolerance in ob/ob mice [PMID:30140027, 36075181].
Leaf extract reduced diarrhea in castor oil-induced and magnesium sulfate-induced animal models [PMID:36791925].
Extract increased osteoblast differentiation, viability, and mineralization, and promoted fracture healing in ovariectomized mice [PMID:38492310, 34799209].
Leaf methanol extract showed hepatoprotective and antioxidant effects in H2O2-induced HepG2 cells [PMID:36567040].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 38731572 (2024) — The Analgesic Potential of Litsea Species: A Systematic Review. · Molecules (Basel, Switzerland)
- 2.PMID: 36678501 (2022) — Ethnomedicinal Uses, Phytochemistry, and Therapeutic Potentials of Litsea glutinosa (Lour.) C. B. Robinson: A Literature-Based Review. · Pharmaceuticals (Basel, Switzerland)
- 3.PMID: 38302935 (2024) — Two rare flavonoid glycosides from Litsea glutinosa (Lour.) C. B. Rob.: experimental and computational approaches endorse antidiabetic potentiality. · BMC complementary medicine and therapies
- 4.PMID: 36567040 (2023) — Hepatoprotective potency of Litsea glutinosa (L.) C.B. Rob. leaf methanol extract on H2O2-induced toxicity in HepG2 cells. · Journal of ethnopharmacology
- 5.PMID: 38492310 (2024) — Litsea glutinosa extract promotes fracture healing and prevents bone loss via BMP2/SMAD1 signaling.