PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Os Draconis is reported to effectively treat insomnia and anxiety [PMID:41368289].
Adjuvant treatment with Chai-Hu-Jia-Long-Gu-Mu-Li-Tang (CHJLGMLT) combined with western therapy significantly reduced Tinnitus Handicap Inventory (THI) and Pittsburgh Sleep Quality Index (PSQI) scores compared to western therapy alone [PMID:25847560].
Carbon dots derived from Os Draconis (OD-CDs) demonstrated anxiolytic effects in mice across four behavioral tests (OFT, LDT, EPMT, and NSFT) [PMID:36275482].
Evidence summary
PubMed sources
- 1.PMID: 41672119 (2026) — Long Gu (Os Draconis): Textual research, modern scientific evaluation, and quality control challenges. · Journal of ethnopharmacology
- 2.PMID: 36275482 (2022) — Carbon Dots Derived from Os Draconis and Their Anxiolytic Effect. · International journal of nanomedicine
- 3.PMID: 28220276 (2017) — Taxonomic examination of longgu (Fossilia Ossis Mastodi, "dragon bone") and a related crude drug, longchi (Dens Draconis, "dragon tooth"), from Japanese and Chinese crude drug markets. · Journal of natural medicines
- 4.PMID: 41368289 (2025) — Os Draconis-Derived Nanoparticles Improve Insomnia Symptoms by Activating Calcium-Dependent 5-HT Release and the Vagal-NTS Pathway. · International journal of nanomedicine
- 5.PMID: 40976904