PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Feeding a polyphenolic extract markedly alleviated hepatomegaly and hepatic triglyceride accumulation [PMID:22067945]
Lotus polyphenol normalized gene expression of IL-1α and mRNA levels of MMP-1 in human keratinocyte cells [PMID:35464168]
The peptide EWGHLGL reduced ROS in HaCaT cells and enhanced SOD and CAT activity while decreasing MDA levels in mouse liver tissues [PMID:40876165]
Evidence summary
PubMed sources
- 1.PMID: 37866555 (2023) — Modifications of native lotus (Nelumbo nucifera G.) rhizome starch and its overall characterization: A review. · International journal of biological macromolecules
- 2.PMID: 34358960 (2022) — Comprehensive characterization of lotus root polysaccharide-phenol complexes. · Food chemistry
- 3.PMID: 40876165 (2025) — Discovery and functional validation of a novel lotus root-derived peptide (EWGHLGL) alleviating oxidative stress in vitro and in vivo. · Food chemistry
- 4.PMID: 35464168 (2022) — Lotus root extract inhibits skin damage through suppression of collagenase production in vitro. · Cytotechnology
- 5.PMID: 22067945 (2011) — Polyphenolic extract of lotus root (edible rhizome of Nelumbo nucifera) alleviates hepatic steatosis in obese diabetic db/db mice.