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Machilus thunbergii
Evergreen tree of coastal East Asia from Japan to China with large leaves, used in traditional Japanese and Chinese medicine.
Evergreen tree of coastal East Asia from Japan to China with large leaves, used in traditional Japanese and Chinese medicine. Key active compounds include machilin, magnolenin, flavonoids.
machilin, along with magnolenin and flavonoids, are the primary bioactive compounds in Machilus thunbergii. These compounds modulates NF-κB and COX-2 inflammatory pathways, disrupts microbial cell membranes and inhibits pathogen growth, acts on pain pathways via anti-inflammatory and neuroactive effects.
Anti-inflammatory
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Analgesic
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Antimicrobial
Wound healing
Traditional Japanese Kampo medicine for pain and inflammation
Based on traditional use; clinical evidence limited
Used in Chinese folk medicine for rheumatism and skin conditions
Based on traditional use; clinical evidence limited
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