PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Active compounds
Mechanism of action
Clinical evidence
Anthocyanin extracts from crabapple fruit, specifically cyanidin 3-O-galactoside, alleviate the severity of mastitis and blood milk barrier damage in cows, goats, and mice by inhibiting PANoptosis activation [PMID:40552401]
Evidence summary
PubMed sources
- 1.PMID: 40552401 (2025) — Anthocyanins Prevent Mastitis Exacerbation by Inhibiting PANoptosis Activation. · Advanced science (Weinheim, Baden-Wurttemberg, Germany)
- 2.PMID: 37148364 (2023) — Ecological and evolutionary drivers of phenotypic and genetic variation in the European crabapple [Malus sylvestris (L.) Mill.], a wild relative of the cultivated apple. · Annals of botany
- 3.PMID: 36874569 (2022) — The genome sequence of the European crab apple, Malus sylvestris  (L.) Mill., 1768. · Wellcome open research
- 4.PMID: 24290193 (2014) — The domestication and evolutionary ecology of apples. · Trends in genetics : TIG
- 5.PMID: 33145002 (2020) — Genetic integrity is still maintained in natural populations of the indigenous wild apple species Malus sylvestris (Mill.) in Saxony as demonstrated with nuclear SSR and chloroplast DNA markers.