PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 7 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Genistein, a flavonoid derivative of M. reticulata, showed the strongest inhibitory activity against SK-Hep-1 human hepatocellular carcinoma cells with an IC(50) value of 16.23 microM [PMID:19994890].
Oral administration of water extracts of M. reticulata Benth (WEMRB) or protocatechuic acid (PCA) significantly lowered serum levels of hepatic enzyme markers (AST and ALT) and reduced cytoplasmic vacuolization and necrosis in rats [PMID:19735183].
Evidence summary
PubMed sources
- 1.PMID: 19994890 (2010) — Anticancer effects of flavonoid derivatives isolated from Millettia reticulata Benth in SK-Hep-1 human hepatocellular carcinoma cells. · Journal of agricultural and food chemistry
- 2.PMID: 19735183 (2009) — Protective effect of Millettia reticulata Benth against CCl(4)-induced hepatic damage and inflammatory action in rats. · Journal of medicinal food