PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Ethanolic extract of seeds (ES) and isolated triterpenoids decreased plasma total cholesterol by 15%-20% in hamsters [PMID:32162705].
Butanol extracts attenuated oxonic acid potassium salt-induced hyperuricaemia in mice by lowering serum uric acid levels [PMID:26821007].
Oral administration of miracle fruit improved insulin sensitivity and decreased plasma glucose in fructose-rich chow-fed rats [PMID:16941611].
Leaf extract inhibited the growth of MCF-7 xenograft tumors in mice and showed antiangiogenesis activity in zebrafish [PMID:36046137].
A randomized, double-blind, placebo-controlled trial assessed the safety and efficacy of seed oil (MFSO) in reducing hair breakage in women [PMID:29399260].
Pregnancy & lactation
Evidence summary
PubMed sources
- 1.PMID: 33177634 (2020) — Phenotypic variation, functional traits repeatability and core collection inference in Synsepalum dulcificum (Schumach & Thonn.) Daniell reveals the Dahomey Gap as a centre of diversity. · Scientific reports
- 2.PMID: 32162705 (2020) — The cholesterol-lowering activity of miracle fruit (Synsepalum dulcificum). · Journal of food biochemistry
- 3.PMID: 33426338 (2020) — Nutritional benefits, phytochemical constituents, ethnomedicinal uses and biological properties of Miracle fruit plant (Synsepalum dulcificum Shumach. & Thonn. Daniell). · Heliyon
- 4.PMID: 35046985 (2021) — The Chromosome-Level Genome of Miracle Fruit (Synsepalum dulcificum) Provides New Insights Into the Evolution and Function of Miraculin. · Frontiers in plant science
- 5.PMID: 25314134