PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Seed oil extract significantly reduced egg numbers, granuloma size, and liver histopathology while decreasing pro-inflammatory cytokines [PMID:39494757].
Seed oil supplementation abrogated neurotoxicity by inhibiting cholinesterase, oxidative stress, and anti-inflammatory mechanisms [PMID:31353570].
Methanol extracts showed potent anticancer effects toward Caco-2, MDA, and HepG-2 cells, inducing apoptosis in tumor cells [PMID:38955793].
Ethanolic extract of seed oil provided hepatoprotective and renoprotective effects [PMID:35947842].
Seed extract and purified MIC-1 mitigated inflammation and oxidative stress in a TPA-induced ear edema model [PMID:38037612].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 39494757 (2024) — Schistosomicidal Effects of Moringa oleifera Seed Oil Extract on Schistosoma mansoni-Infected Mice. · Parasite immunology
- 2.PMID: 31353570 (2019) — Moringa oleifera seed oil or virgin coconut oil supplementation abrogates cerebral neurotoxicity induced by antineoplastic agent methotrexate by suppression of oxidative stress and neuro-inflammation in rats. · Journal of food biochemistry
- 3.PMID: 39554357 (2024) — Antioxidant, anticancer, and anti-inflammatory potential of Moringa seed and Moringa seed oil: A comprehensive approach. · Food science & nutrition
- 4.PMID: 31289640 (2019) — Treatments and uses of Moringa oleifera seeds in human nutrition: A review. · Food science & nutrition
- 5.PMID: 36047239