PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
A split-face clinical study using a combination of Empetrum nigrum fruit juice and Betula alba bark extract showed significantly better skin restructuring and corneocyte cohesion compared to placebo [PMID:36293365]
Crowberry extracts inhibited cell proliferation and migration through the inhibition of DEK and Akt signaling [PMID:35698073]
Ethanol extracts of E. nigrum var. japonicum significantly inhibited tube formation and proliferation of HUVECs and showed antiangiogenic activity in chick embryo CAM assays [PMID:27396205]
Evidence summary
PubMed sources
- 1.PMID: 27941619 (2016) — Black Crowberry (Empetrum nigrum L.) Flavonoids and Their Health Promoting Activity. · Molecules (Basel, Switzerland)
- 2.PMID: 34030545 (2022) — Nigrumol A, a new triterpenoid from Empetrum nigrum subsp. asiaticum (Nakai ex H.Ito) Kuvaev. · Natural product research
- 3.PMID: 18522397 (2008) — Anthocyanin composition and antioxidant activity of the Crowberry (Empetrum nigrum) and other berries. · Journal of agricultural and food chemistry
- 4.PMID: 39279794 (2024) — Population re-establishment and spatial dynamics of crowberry (Empetrum nigrum ssp. hermaphroditum), a foundation species in restored alpine ecosystems. · Ecology and evolution
- 5.PMID: 40902362 (2025)