PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 11 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Ethanolic extracts of O. bullata demonstrated high inhibitory activity against prostaglandin synthesis in vitro [PMID:8735453].
Bark and leaf extracts showed inhibitory activity in cyclooxygenase-1 and 5-lipoxygenase test systems, with fresh leaf extracts being superior to bark extracts [PMID:10904166].
Stem bark extracts were evaluated for inhibitory activity against α-amylase and α-glucosidase [PMID:29526237].
Evidence summary
PubMed sources
- 1.PMID: 10904166 (2000) — Analytical and pharmacological investigation of Ocotea bullata (black stinkwood) bark and leaves. · Journal of ethnopharmacology
- 2.PMID: 8735453 (1996) — Screening of Zulu medicinal plants for prostaglandin-synthesis inhibitors. · Journal of ethnopharmacology
- 3.PMID: 29526237 (2018) — Medicinal properties of Ocotea bullata stem bark extracts: phytochemical constituents, antioxidant and anti-inflammatory activity, cytotoxicity and inhibition of carbohydrate-metabolizing enzymes. · Journal of integrative medicine
- 4.PMID: 10904175 (2000) — Plant part substitution--a way to conserve endangered medicinal plants? · Journal of ethnopharmacology
- 5.PMID: 10940585 (2000)