PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Ingestion of 500 g of broiled nopal stems significantly decreased serum glucose (mean reduction 16.2-17.6% of basal values at 180 min) and serum insulin levels [PMID: 3276479].
Broiled stems caused a significant decrease in serum glucose (41 to 46% less than initial value), while crude extracts did not cause a significant decrease [PMID: 1844121, PMID: 2488772].
Fruit extracts significantly attenuated injury markers in male Wistar rats and hepatocyte cultures [PMID: 27782042, PMID: 33233135].
Extracts inhibited intracellular and extracellular replication of DNA and RNA viruses, including HIV and herpes simplex virus [PMID: 8783800].
Safety & adverse effects
Dosage & administration
Evidence summary
PubMed sources
- 1.PMID: 37371904 (2023) — Beneficial Effects of Opuntia spp. on Liver Health. · Antioxidants (Basel, Switzerland)
- 2.PMID: 27782042 (2016) — Hepatoprotective Effect of Opuntia robusta and Opuntia streptacantha Fruits against Acetaminophen-Induced Acute Liver Damage. · Nutrients
- 3.PMID: 3276479 (1988) — Hypoglycemic effect of Opuntia streptacantha Lemaire in NIDDM. · Diabetes care
- 4.PMID: 17493807 (2008) — Experimental binding of lead to a low cost on biosorbent: Nopal (Opuntia streptacantha). · Bioresource technology
- 5.PMID: 37143992 (2023) — Predicting geographic distribution and habitat suitability of Opuntia streptacantha in paleoclimatic, current, and future scenarios in Mexico.