PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 6 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Crude root extracts showed antiplasmodial activity with an IC50 of 15.6-31.2 microg/ml [PMID:20189612] and a MIC of 31.25 microg/mL [PMID:19653145].
Isoflavones and biflavonoids from the stem bark and roots demonstrated cytotoxicity towards cancer cells [PMID:30836216].
Evidence summary
PubMed sources
- 1.PMID: 30836216 (2019) — Cytotoxicity of isoflavones and biflavonoids from Ormocarpum kirkii towards multi-factorial drug resistant cancer. · Phytomedicine : international journal of phytotherapy and phytopharmacology
- 2.PMID: 20189612 (2010) — Antiplasmodial activity of (I-3,II-3)-biflavonoids and other constituents from Ormocarpum kirkii. · Phytochemistry
- 3.PMID: 21328178 (2011) — Herbal medicines and infectious diseases: characterization by LC-SPE-NMR of some medicinal plant extracts used against malaria. · Planta medica
- 4.PMID: 22575670 (2012) — Rapid isolation and identification of minor natural products by LC-MS, LC-SPE-NMR and ECD: isoflavanones, biflavanones and bisdihydrocoumarins from Ormocarpum kirkii. · Phytochemistry
- 5.PMID: 27988077