PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Stem bark decoctions showed antidiarrheal activity and induced dose-dependent relaxation of isolated rat ileum fragments [PMID:39683945]
Xanthones isolated from stem bark and fruit pericarp exhibited potent antiplasmodial activity in vitro [PMID:19296616, PMID:20927694]
Certain xanthones from the stem bark demonstrated potent cytotoxicity in vitro [PMID:19296616]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 25523343 (2015) — Profiling the quality characteristics of the butter of Pentadesma butyracea with reference to shea butter. · Journal of the science of food and agriculture
- 2.PMID: 39683945 (2024) — Phytochemical Analysis and Antidiarrheal Activity of Stem Bark Decoctions of Pentadesma butyracea Sabine (Clusiaceae). · Molecules (Basel, Switzerland)
- 3.PMID: 38370066 (2024) — New value chain Pentadesma nuts and butter from West Africa to international markets: Biological activities, health benefits, and physicochemical properties. · Food science & nutrition
- 4.PMID: 19296616 (2009) — Cytotoxic and antiplasmodial xanthones from Pentadesma butyracea. · Journal of natural products
- 5.PMID: 41929262 (2026)