PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Active compounds
Mechanism of action
Clinical evidence
Ethanolic extract of Tacca tubers demonstrated inhibitory activity of HMG Co-A reductase in vitro (IC50 value of 4.92 ppm), with stigmasterol showing high binding affinity [PMID:36500698]
Isolated taccalonolides from T. leontopetaloides tubers exhibited in vitro antitrypanosomal activity with EC50 values starting from 0.79 μg/mL [PMID:27313159]
Evidence summary
PubMed sources
- 1.PMID: 17221399 (1990) — Steroidal Sapogenins from Tacca leontopetaloides. · Planta medica
- 2.PMID: 36500698 (2022) — In Silico and In Vitro Analysis of Tacca Tubers (Tacca leontopetaloides) from Banyak Island, Aceh Singkil Regency, Indonesia, as Antihypercholesterolemia Agents. · Molecules (Basel, Switzerland)
- 3.PMID: 27313159 (2016) — Antitrypanosomal Activity of a Novel Taccalonolide from the Tubers of Tacca leontopetaloides. · Phytochemical analysis : PCA
- 4.PMID: 40509356 (2025) — Antitrypanosomal and Antileishmanial Activities of Tacca leontopetaloides Tubers and Zanthoxylum zanthoxyloides Stem Bark. · Molecules (Basel, Switzerland)