PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 23 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Used for the treatment of hemorrhoids and piles [PMID:22390207]
A case report of a 36-year-old woman developed acute hepatitis and jaundice after consuming lesser celandine extract for hemorrhoids for approximately 10 days [PMID:25729484]. Another report noted acute necrotizing hepatitis in patients taking herbal remedies containing common or lesser celandine [PMID:9856112].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 25729484 (2015) — Lesser celandine (pilewort) induced acute toxic liver injury: The first case report worldwide. · World journal of hepatology
- 2.PMID: 22390207 (2012) — Ficaria verna Huds. extracts and their β-cyclodextrin supramolecular systems. · Chemistry Central journal
- 3.PMID: 12132681 (2002) — Flavonoids from Ficaria verna Huds. · Zeitschrift fur Naturforschung. C, Journal of biosciences
- 4.PMID: 12533962 (2002) — Composition of lipophylic extracts from Ficaria verna HUDS. flowers. · Roczniki Akademii Medycznej w Bialymstoku (1995)
- 5.PMID: 9856112 (1998) — [Necrotizing hepatitis after taking herbal remedies].