PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Hydroalcoholic extract (SeHA) significantly decreased systolic blood pressure in mice and showed an antihypertensive effect greater than losartan [PMID:20488233]
Hydroalcoholic extracts and isolated compounds (such as isosakuranetin-5-O-rutinoside) induced anxiolytic and antidepressant-like effects in mice and rats, as evidenced by the forced swimming test and elevated plus-maze [PMID:16413718, PMID:16530995, PMID:24165584, PMID:34568977]
Secoisopimaranes from leaves showed potent antimicrobial activity against Staphylococcus aureus (MIC = 15.6 µg/mL) [PMID:41062670]
S. elegans decoction was found to be an effective inhibitor of α-glucosidase [PMID:30513773]
Drug interactions
Evidence summary
PubMed sources
- 1.PMID: 32347111 (2021) — Angiotensin-converting enzyme inhibitors from Salvia elegans Vahl. · Natural product research
- 2.PMID: 34568977 (2021) — Antidepressant and anxiolytic compounds isolated from Salvia elegans interact with serotonergic drugs. · Naunyn-Schmiedeberg's archives of pharmacology
- 3.PMID: 41062670 (2025) — Secoisopimaranes from Salvia elegans Vahl leaves as antibacterial agents against Staphylococcus aureus. · Scientific reports
- 4.PMID: 30513773 (2018) — Salvia elegans, Salvia greggii and Salvia officinalis Decoctions: Antioxidant Activities and Inhibition of Carbohydrate and Lipid Metabolic Enzymes. · Molecules (Basel, Switzerland)
- 5.PMID: 39274918 (2024)