PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Plantago major seed powder, when administered as 10 gm sachets twice daily for 60 days alongside standard treatment (Losartan), significantly reduced proteinuria [PMID:38797623].
A case-control study compared 10% P. major ointment to 1% silver sulfadiazine for the healing of second-degree burns [PMID:35966146].
P. major extract demonstrated significant antimicrobial activity against Streptococcus mutans, although the inhibition zones were smaller than those of chlorhexidine [PMID:41538511].
Reviews indicate the plant is effective as a wound healer, anti-inflammatory, antibacterial, and antiviral agent [PMID:29028587, PMID:37631007].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 15283880 (2004) — Biology of weed pollen allergens. · Current allergy and asthma reports
- 2.PMID: 29028587 (2017) — Chemical constituents and medical benefits of Plantago major. · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
- 3.PMID: 37631007 (2023) — Antimicrobial and Other Biomedical Properties of Extracts from Plantago major, Plantaginaceae. · Pharmaceuticals (Basel, Switzerland)
- 4.PMID: 29629064 (2018) — Plantago major in Traditional Persian Medicine and modern phytotherapy: a narrative review. · Electronic physician
- 5.PMID: 38797623 (2024) — Efficacy and safety of Plantago major seeds in patients with diabetic nephropathy: A randomized open-labeled controlled clinical trial. · Explore (New York, N.Y.)