PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 29 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Oral administration of isolated PAPN1 (10, 20, and 40 mg/kg/day) significantly reduced renal calcium oxalate crystal deposition in a dose-dependent manner and improved renal function in vivo [PMID:41679836]
Extract efficiently re-epithelized wounds generated on mice by accelerating the migration of HaCaT keratinocytes [PMID:26929003]
Extract reduced fatigue and attenuated symptoms in a mouse model of restraint stress [PMID:29655685]
Extract and quercetin inhibit precontraction in mouse and human airway smooth muscle [PMID:29449621]
Herbal extract (50 mg/kg) was evaluated for its ability to diminish hazardous effects of EMF exposure in mice [PMID:22308654]
Evidence summary
PubMed sources
- 1.PMID: 31644102 (2012) — The genome sequence of common knotgrass, Polygonum aviculare L. (Polygonaceae). · CITED REFERENCE
- 2.PMID: 31792306 (2019) — Inhibitory characteristics of flavonol-3-O-glycosides from Polygonum aviculare L. (common knotgrass) against porcine pancreatic lipase. · Scientific reports
- 3.PMID: 29449621 (2018) — Polygonum aviculare L. extract and quercetin attenuate contraction in airway smooth muscle. · Scientific reports
- 4.PMID: 39683107 (2024) — Hydroethanolic Extract of Polygonum aviculare L. Mediates the Anti-Inflammatory Activity in RAW 264.7 Murine Macrophages Through Induction of Heme Oxygenase-1 and Inhibition of Inducible Nitric Oxide Synthase. · Plants (Basel, Switzerland)
- 5.PMID: 35464762