PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Blackthorn juice significantly reduced the viability of AGS and KATO III gastric cancer cells in vitro while sparing non-tumorigenic GES-1 cells [PMID:41085359]
Dried blackthorn fruit powder was evaluated for protective effects on the blood and organs of albino Wistar rats exposed to tartrazine [PMID:31417987]
In C57BL/6 mice, blackthorn flower extract increased glucose concentrations in normoglycaemic mice after the 1st and 5th day of administration [PMID:34759766]
Methanol extract of P. spinosa fruit was evaluated for in vitro cytotoxic activity on multiform brain cancer (LN229, U87, T98G) and pancreas cancer (PANC-1, AsPC-1) cell lines [PMID:32821452]
Evidence summary
PubMed sources
- 1.PMID: 37110690 (2023) — Blackthorn-A Valuable Source of Phenolic Antioxidants with Potential Health Benefits. · Molecules (Basel, Switzerland)
- 2.PMID: 36543000 (2023) — An arabinan isolated from the antioxidant active fraction of wild blackthorn fruits (Prunus spinosa L.). · Carbohydrate research
- 3.PMID: 31417987 (2019) — Protective effect of blackthorn fruits (Prunus spinosa) against tartrazine toxicity development in albino Wistar rats. · BMC chemistry
- 4.PMID: 32821452 (2019) — Antioxidant Activity of Blackthorn (Prunus spinosa L.) Fruit Extract and Cytotoxic Effects on Various Cancer Cell Lines. · Medeniyet medical journal
- 5.PMID: 37627632 (2023) — Technologically Driven Approaches for the Integrative Use of Wild Blackthorn (Prunus spinosa L.) Fruits in Foods and Nutraceuticals.