PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Root extract (EPP) suppressed cell growth and colony formation and triggered apoptosis regardless of EGFR mutation or TKI resistance status in vitro [PMID:35408753]
Praeruptorin A alleviated symptoms of DSS-induced acute ulcerative colitis, reduced inflammatory factors, and repaired intestinal barrier function [PMID:40924655]
Leaf aqueous extract protected against gastric injury by inhibiting inflammation and oxidative stress [PMID:39053717]
Extract (PPDE) showed antioxidant capacity by scavenging DPPH, ABTS, hydroxyl, and superoxide anion radicals, improving cell survival after H2O2 treatment [PMID:37860131]
Evidence summary
PubMed sources
- 1.PMID: 38633612 (2024) — The traditional uses, pharmacology, and phytochemistry of Peucedanum praeruptorum Dunn. · Frontiers in pharmacology
- 2.PMID: 37723451 (2023) — Genome sequencing-based transcriptomic analysis reveals novel genes in Peucedanum praeruptorum. · BMC genomic data
- 3.PMID: 33366108 (2019) — The complete plastome of Peucedanum praeruptorum (Apiaceae). · Mitochondrial DNA. Part B, Resources
- 4.PMID: 37992933 (2024) — A chromosome-scale genome of Peucedanum praeruptorum provide insights into Apioideae evolution and medicinal ingredient biosynthesis. · International journal of biological macromolecules
- 5.PMID: 35408753 (2022) — The Root Extract of Peucedanum praeruptorum Dunn Exerts Anticancer Effects in Human Non-Small-Cell Lung Cancer Cells with Different EGFR Mutation Statuses by Suppressing MET Activity.