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PubMed · Ethanolic Extracts of <i>Artemisia apiacea</i> Hance Improved Atopic Dermatitis-Like Skin Lesions In Vivo and Suppressed TNF-Alpha/IFN-Gamma⁻Induced Proinflammatory Chemokine Production In Vitro. (2018)
PubMed · Anti-allergic effect of <i>Artemisia</i> extract in rats. (2016)
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This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 18 PubMed articles · model: gemma4:31b
Summary
Artemisia apiacea is a traditional medicinal plant native to Eastern Asia used for treating conditions such as malaria, eczema, and jaundice [PMID: 29932162, 24250718, 38612399].
Background
Artemisia apiacea Hance is a traditional herbal medicine native to China, Japan, and Korea [PMID: 29932162, 38612399].
Traditional uses
Traditional uses include the treatment of malaria and malaria-like diseases [PMID: 29504922, 24250718], eczema [PMID: 29932162, 25829768], jaundice [PMID: 29932162, 24250718], and dyspeptic complaints [PMID: 24250718].
The herb exhibits anti-inflammatory effects by inhibiting NF-κB activation and reducing the expression of iNOS, COX-2, TNF-α, IL-1β, and IL-6 [PMID: 24250718]. In atopic dermatitis models, it suppresses the production of RANTES, IL-6, IL-8, and TARC by inhibiting p38, ERK, and STAT-1 activation [PMID: 29932162]. Vitexicarpin induces apoptosis in osteosarcoma cells via the AKT-PRAS40 pathway [PMID: 38612399]. Polysaccharides from the plant induce cell apoptosis and immunomodulation [PMID: 24653548].
Clinical evidence
Evidence DAtopic Dermatitis
Ethanolic extracts improved atopic dermatitis-like skin lesions in vivo [PMID: 29932162]
Evidence DAllergic Reaction
Extracts from dried flowering tips showed anti-allergic effects in rats by reducing systemic anaphylactic shock and histamine release [PMID: 27446332]
Evidence DHepatoma
Polysaccharides inhibited hepatoma growth in tumour-bearing mice [PMID: 24653548]
Evidence DOsteosarcoma
Vitexicarpin induced dose- and time-dependent cell death in human osteosarcoma MG63 cells via apoptosis [PMID: 38612399]
Evidence DAntimicrobial
Extracts were effective in vitro against A. niger, C. albicans, B. subtilis, and S. aureus [PMID: 29504922]
Evidence summary
The current evidence is primarily based on in vitro studies and animal models (Level D), demonstrating significant anti-inflammatory, antioxidant, and anti-tumor potential, though clinical human trials are lacking in the provided data.
PubMed sources
1.PMID: 27446332 (2016) — Anti-allergic effect of Artemisia extract in rats. · Experimental and therapeutic medicine
2.PMID: 29932162 (2018) — Ethanolic Extracts of Artemisia apiacea Hance Improved Atopic Dermatitis-Like Skin Lesions In Vivo and Suppressed TNF-Alpha/IFN-Gamma⁻Induced Proinflammatory Chemokine Production In Vitro. · Nutrients
3.PMID: 29504922 (2018) — Evaluation of in-vitro antimicrobial activity of Artemisia apiacea H. and Scutellaria baicalensis G. extracts. · Journal of medical microbiology
4.PMID: 38612399 (2024) — Vitexicarpin Induces Apoptosis and Inhibits Metastatic Properties via the AKT-PRAS40 Pathway in Human Osteosarcoma. · International journal of molecular sciences
No direct government monograph is available for this herb. The content below is AI-generated and has not been verified against an authoritative government source. Use the search links to check official sources before relying on this information.
— Coronaviruses and Nature's Pharmacy for the Relief of Coronavirus Disease 2019.
· Revista brasileira de farmacognosia : orgao oficial da Sociedade Brasileira de Farmacognosia
6.PMID: 25829768 (2015) — Simultaneous determination three phytosterol compounds, campesterol, stigmasterol and daucosterol in Artemisia apiacea by high performance liquid chromatography-diode array ultraviolet/visible detector. · Pharmacognosy magazine
7.PMID: 12048024 (2002) — Arteminin, a new coumarin from Artemisia apiacea. · Fitoterapia
8.PMID: 12576204 (2003) — Anti-oxidant activities of the extracts from the herbs of Artemisia apiacea. · Journal of ethnopharmacology
9.PMID: 24250718 (2013) — Methanol Extract of Artemisia apiacea Hance Attenuates the Expression of Inflammatory Mediators via NF- κ B Inactivation. · Evidence-based complementary and alternative medicine : eCAM
10.PMID: 12135098 (2002) — Phytochemical constituents from the herba of Artemisia apiacea. · Archives of pharmacal research
11.PMID: 18348053 (2008) — Artemisterol, a new steryl ester from the whole plant of Artemisia apiacea. · Journal of Asian natural products research
12.PMID: 14661854 (2003) — Constituents from the non-polar fraction of Artemisia apiacea. · Archives of pharmacal research
13.PMID: 24653548 (2014) — Anti-tumour effects of polysaccharides isolated from Artemisia annua L by inducing cell apoptosis and immunomodulatory anti-hepatoma effects of polysaccharides. · African journal of traditional, complementary, and alternative medicines : AJTCAM
14.PMID: 25392593 (2014) — Combinative effects of thanh hao miet giap thang (sweet wormwood and tortoise shell decoction) ingredients on antioxidative activity in vitro. · African journal of traditional, complementary, and alternative medicines : AJTCAM
15.PMID: 28670366 (2017) — Inhibitory effect of dihydroartemisinin on chondrogenic and hypertrophic differentiation of mesenchymal stem cells. · American journal of translational research
16.PMID: 33145645 (2021) — Electrochemical determination of artemisinin based on signal inhibition for the reduction of hemin. · Analytical and bioanalytical chemistry