PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Ethanolic extract of pods inhibited HMG-CoA reductase by 67.1% in vitro and showed potential for regression of atherosclerotic plaques in rabbits [PMID:31931807]
Methanol extract of stem bark showed nootropic activity in rats via Morris water-maze testing and AChE inhibition [PMID:22906223]; ethyl acetate fraction of bark ameliorated AlCl3-induced Alzheimer's pathology in rats [PMID:41421404]
Aqueous bark extract (400 mg/kg) reduced defecation frequency by 57.29% and inhibited charcoal meal transit by 89.11% in rats [PMID:40726568]
Khejri was used as a dietary supplement (500 mg daily) in cricket players to investigate effects on lipid profile and physical fitness [PMID:36726398]
Vitexin isolated from leaves exhibited cytotoxicity by reducing mitochondrial membrane potential and causing DNA fragmentation [PMID:34109977]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 29086686 (2018) — Ethnopharmacological and Phytopharmaceutical Evaluation of Prosopis cineraria: An Overview and Future Prospects. · Current drug metabolism
- 2.PMID: 35955640 (2022) — The Genome of the Mimosoid Legume Prosopis cineraria, a Desert Tree. · International journal of molecular sciences
- 3.PMID: 22906223 (2012) — Prosopis cineraria: a potential nootropic agent. · Pharmaceutical biology
- 4.PMID: 41095111 (2025) — Population Genomics and Genetic Diversity of Prosopis cineraria in the United Arab Emirates: Insights for Conservation in Arid Ecosystems. · Plants (Basel, Switzerland)
- 5.PMID: 31931807 (2020) — Phytoconstituents of an ethanolic pod extract of Prosopis cineraria triggers the inhibition of HMG-CoA reductase and the regression of atherosclerotic plaque in hypercholesterolemic rabbits.