PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
A study on adults at risk for cardiovascular disease investigated effects on biochemical and oxidative stress parameters [PMID:20833235].
Rooibos extract significantly decreased ROS production and pro-inflammatory cytokine secretion in human leukocytes [PMID:37049592].
Pre-clinical data suggests a supporting role in preventing neurodegeneration via anti-oxidative and anti-inflammatory properties [PMID:35311618].
In vitro studies indicate rooibos and quercetin can suppress ovarian cell functions, promote apoptosis markers, and reduce proliferation markers [PMID:37159860]. In male rats, unfermented rooibos enhanced sperm concentration, viability, and motility [PMID:24007336].
Rooibos is traditionally considered to have antispasmodic and anti-inflammatory effects in the gut; zebrafish models were used to evaluate these claims [PMID:37923252].
Safety & adverse effects
Drug interactions
Evidence summary
PubMed sources
- 1.PMID: 38204815 (2023) — The health benefits of rooibos tea in humans (aspalathus linearis)-a scoping review. · Journal of public health in Africa
- 2.PMID: 37049592 (2023) — Aspalathus linearis (Rooibos) Targets Adipocytes and Obesity-Associated Inflammation. · Nutrients
- 3.PMID: 35311618 (2023) — Pharmacological activity of Aspalathus linearis extracts: pre-clinical research in view of prospective neuroprotection. · Nutritional neuroscience
- 4.PMID: 34402103 (2022) — Rooibos (Aspalathus linearis) influence on health and ovarian functions. · Journal of animal physiology and animal nutrition
- 5.PMID: 35850312 (2022) — Rooibos (Aspalathus linearis) alters secretome trace amine profile of probiotic and commensal microbes in vitro.