PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Demonstrated positive effects in attenuating dyslipidemia, obesity, diabetes, and hypertension [PMID:38004453]
Oral administration of sacha inchi oil attenuated hyperglycemia and insulin resistance indices and improved hepatic histopathological alterations in a dose-dependent manner [PMID:37066030]
Ethanol extract of leaves showed anti-arthritis effects in a complete Freund's adjuvant-induced model [PMID:37860100]
Oil exhibits cellular antioxidant activity with inhibitory effects against MMP-2 and is safe for human fibroblast cells at 1-3% concentrations [PMID:38171737]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 35548366 (2022) — Vegetable Butters and Oils as Therapeutically and Cosmetically Active Ingredients for Dermal Use: A Review of Clinical Studies. · Frontiers in pharmacology
- 2.PMID: 29884388 (2018) — Sacha inchi (Plukenetia volubilis L.): Nutritional composition, biological activity, and uses. · Food chemistry
- 3.PMID: 38998552 (2024) — Sacha Inchi (Plukenetia volubilis L.) Protein Hydrolysate as a New Ingredient of Functional Foods. · Foods (Basel, Switzerland)
- 4.PMID: 39484157 (2024) — The application prospects of sacha inchi (Plukenetia volubilis linneo) in rheumatoid arthritis. · Frontiers in pharmacology
- 5.PMID: 34731811 (2022) — Sacha inchi (Plukenetia volubilis L.): An emerging source of nutrients, omega-3 fatty acid and phytochemicals.