PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Oral elderberry syrup (15 ml four times daily for 5 days) relieved symptoms on average 4 days earlier and significantly reduced the use of rescue medication compared to placebo [PMID:15080016].
A standardized extract (Sambucol) reduced the duration of flu symptoms to 3-4 days and was associated with higher antibody levels to the influenza virus in the convalescent phase [PMID:11399518].
Combined supplementation of 100 mg elderberry extract with lutein and zeaxanthin for 20 days significantly improved Ocular Surface Disease Index (OSDI) scores [PMID:39770987].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 15080016 (2004) — Randomized study of the efficacy and safety of oral elderberry extract in the treatment of influenza A and B virus infections. · The Journal of international medical research
- 2.PMID: 38998923 (2024) — Development of Potential Therapeutic Agents from Black Elderberries (the Fruits of Sambucus nigra L.). · Molecules (Basel, Switzerland)
- 3.PMID: 19548290 (2010) — A systematic review on the sambuci fructus effect and efficacy profiles. · Phytotherapy research : PTR
- 4.PMID: 28198157 (2017) — A Review of the Antiviral Properties of Black Elder (Sambucus nigra L.) Products. · Phytotherapy research : PTR
- 5.PMID: 11399518 (2001) — The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines.