PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Sang-Bai-Pi extract and regiafuran C ameliorate renal fibrosis in a unilateral ureteral obstruction rat model [PMID:39756310]
Methanolic extract reduced serum amylase, lipase, and caspase-1 levels in alcohol and cerulein-induced pancreatitis rat models [PMID:30302330, 30335608]
Ethyl acetate fractions reduced heart weight and lowered serum renin and angiotensinogen levels in high-salt diet mice [PMID:38790847]
Extracts inhibited the proliferation of human colorectal (HCT116, SW480, LoVo) and breast (MDA-MB-231, MCF-7) cancer cells in vitro [PMID:26926171]
Prenylated flavanones from the root bark exhibit α-glucosidase inhibitory activity [PMID:39102223, 38147942]
Evidence summary
PubMed sources
- 1.PMID: 39756310 (2025) — Sang-Bai-Pi extract and its constituent regiafuran C ameliorate renal fibrosis through TGF-β/Smad and Wnt/β-catenin signaling pathways. · Phytomedicine : international journal of phytotherapy and phytopharmacology
- 2.PMID: 30470128 (2020) — Anti-inflammatory effects of mulberry (Morus alba L.) root bark and its active compounds. · Natural product research
- 3.PMID: 17405088 (1983) — Constituents of the Chinese crude drug "sāng-bái-pí" (Morus root bark). · Planta medica
- 4.PMID: 39102223 (2024) — Prenylated Flavanone Enantiomers with α-Glucosidase Inhibitory Activity from the Root Bark of Morus alba. · Chemistry & biodiversity
- 5.PMID: 40840729 (2025)