PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 13 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Fractions from Sanicula extract completely inhibited the growth of influenza A/PR/8/34 in MDCK cells, although they did not exhibit direct virucidal activity [PMID:8769089].
Leaf extracts and a specific acidic fraction inhibited HPIV-2 replication in Vero cells without toxic effects [PMID:10441789].
A 50% ethanolic extract of the aerial parts exhibited anti-HIV activity, with rosmarinic acid identified as the principal active substance [PMID:9392884].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 39861619 (2025) — "Radix Saniculae": Phytochemical Characterization and Potential Adulteration of an Austrian Traditional Wound-Healing Agent. · Plants (Basel, Switzerland)
- 2.PMID: 9392884 (1997) — Saniculoside N from Sanicula europaea L. · Journal of natural products
- 3.PMID: 8769089 (1996) — Antiviral effect of Sanicula europaea L. leaves extract on influenza virus-infected cells. · Biochemical and biophysical research communications
- 4.PMID: 38843790 (2024) — VOLKSMED Database: A Source for Forgotten Wound Healing Plants in Austrian Folk Medicine. · Planta medica
- 5.PMID: 10441789 (1999) — Antiviral activity of Sanicula europaea L. extracts on multiplication of human parainfluenza virus type 2.