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Sassafras albidum
This herb is NOT recommended during pregnancy due to potential risks to the developing fetus.
This herb is NOT recommended while breastfeeding as effects on infants are unknown.
Consult your healthcare provider before use.
A Native American tree that was once the second largest export from the New World, now controversial due to safrole content.
A Native American tree that was once the second largest export from the New World, now controversial due to safrole content. Key active compounds include Safrole, Camphor, Asarone.
Safrole, along with Camphor and Asarone, are the primary bioactive compounds in Sassafras. These compounds modulates NF-κB and COX-2 inflammatory pathways.
Anti-inflammatory (safrole-free extracts)
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Diaphoretic
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Historically significant
Blood purification
Based on traditional use; clinical evidence limited
Skin conditions
Based on traditional use; clinical evidence limited
Rheumatism
Based on traditional use; clinical evidence limited
STIs
Based on traditional use; clinical evidence limited
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