PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Sauchinone preserves cardiac function by inhibiting the NLRP3 inflammasome in mouse models [PMID:40068294]
Sauchinone ameliorates IMQ-induced murine psoriasis by regulating macrophage polarization via TGR5 agonism [PMID:40274226]
Extracts suppress ovalbumin-induced airway inflammation by reducing WBCs, neutrophils, and IgE levels [PMID:33024647, PMID:20699114]
Sauchinone inhibits proliferation and induces apoptosis in MCF-7 and Bcap-37 cells by downregulating HER-2 [PMID:36959089]
Extract suppresses cell viability and invasion and induces apoptosis in A498 and ACHN cells [PMID:27909997]
Water extract of leaves was evaluated in type II collagen-induced arthritis mouse models [PMID:30606189]
Evidence summary
PubMed sources
- 1.PMID: 40068294 (2025) — Sauchinone preserves cardiac function in doxorubicin-induced cardiomyopathy by inhibiting the NLRP3 inflammasome. · Phytomedicine : international journal of phytotherapy and phytopharmacology
- 2.PMID: 40274226 (2026) — A novel TGR5 agonist Sauchinone ameliorates IMQ induced murine psoriasis by regulating macrophage polarization. · Journal of advanced research
- 3.PMID: 40709340 (2025) — Therapeutic effects of a combination of Chinese quince and Saururus chinensis extract on allergic airway inflammation in an ovalbumin-induced asthma mouse model. · Frontiers in nutrition
- 4.PMID: 33024647 (2020) — Saururus chinensis-controlled allergic pulmonary disease through NF-κB/COX-2 and PGE2 pathways. · PeerJ
- 5.PMID: 28278686