PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Aqueous extract (200 mg/kg) significantly decreased blood glucose and increased plasma insulin levels in streptozotocin-induced diabetic rats [PMID:15306167, PMID:15296095].
Oral administration of aqueous extract (200 mg/kg) in diabetic rats reduced serum and tissue cholesterol, triglycerides, free fatty acids, and LDL cholesterol [PMID:16579736].
Crude extracts and pure diterpenes showed cytotoxicity against human stomach cancer cell lines [PMID:12880314]; benzoxazinoids showed antiproliferative activity against DU-145 prostate cancer cells [PMID:22944352]; and specific diterpenes showed cytotoxicity against MCF-7 and T47D breast cancer cells [PMID:37630212].
Ethanolic extracts (0.5-1 g/kg) inhibited carrageenan-induced paw edema and reduced acetic acid-induced writhings in rodents [PMID:1841990].
A flavonoid-rich hydroethanolic extract significantly inhibited HSV-1 infectivity in vitro [PMID:41503745].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 27186019 (2016) — Biolistic transformation of Scoparia dulcis L. · Physiology and molecular biology of plants : an international journal of functional plant biology
- 2.PMID: 15306167 (2004) — Insulin-secretagogue activity and cytoprotective role of the traditional antidiabetic plant Scoparia dulcis (Sweet Broomweed). · Life sciences
- 3.PMID: 36875433 (2023) — Chemical constituents from aerial parts of Scoparia dulcis. · Chinese herbal medicines
- 4.PMID: 12880314 (2003) — Cytotoxic diterpenes from Scoparia dulcis. · Journal of natural products
- 5.PMID: 22944352 (2012) — Benzoxazinoids from Scoparia dulcis (sweet broomweed) with antiproliferative activity against the DU-145 human prostate cancer cell line.