PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Used in combination with Gan-Cao to restore differentiation potentials of mesenchymal stem progenitors [PMID:34950216]; used in medicinal-cake-separated moxibustion for senile osteoporosis [PMID:29231606].
Improved learning and memory in rat models by adjusting Glu and GABA content and increasing hippocampal NMDAR1 and GABAR expression [PMID:15015384], and increasing hippocampal NGF and c-fos [PMID:15139152].
A modified Zuo-gui-wan formula containing cooked rehmannia was associated with the restoration of ovulation and conception in a case report [PMID:12956293].
Compatibility of Ginseng and Prepared Rehmannia Root increased the number of peripheral blood and bone marrow nucleated cells in cyclophosphamide-induced mice [PMID:32188797].
Drug interactions
Evidence summary
PubMed sources
- 1.PMID: 39834809 (2024) — Efficacy of the Bushen Jianpi Huoxue Formula on Beclin-1/Bcl-2-mediated autophagy and apoptosis in osteoblasts. · Frontiers in pharmacology
- 2.PMID: 24164386 (2014) — The protective effect of Liu-Wei-Di-Huang-Fang in salt-sensitive hypertension rats. · Clinical and experimental hypertension (New York, N.Y. : 1993)
- 3.PMID: 33849116 (2021) — Network pharmacology study on the mechanism of the herb pair of prepared Rehmannia root-Chinese arborvitae kernel for anxiety disorders. · Annals of palliative medicine
- 4.PMID: 37861529 (2023) — Dissection of action mechanisms of Zuogui Pill in the treatment of liver cancer based on machine learning and network pharmacology: A review. · Medicine
- 5.PMID: 32661660