PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Luffa cylindrica stem sap stimulated the expression of cellular elastin and type I procollagen in human skin fibroblasts in vitro [PMID:35180468]
Luffa fermentation broth (LF) prepared using Lactiplantibacillus plantarum P101 showed a superior protective effect against cyclophosphamide-induced hepatotoxicity compared to unfermented Luffa juice in vivo [PMID:41867061]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 32821411 (2020) — A high-quality sponge gourd (Luffa cylindrica) genome. · Horticulture research
- 2.PMID: 39851721 (2024) — Study on the Vibration Isolation Mechanism of Loofah Sponge. · Biomimetics (Basel, Switzerland)
- 3.PMID: 35260602 (2022) — A SNP of betaine aldehyde dehydrogenase (BADH) enhances an aroma (2-acetyl-1-pyrroline) in sponge gourd (Luffa cylindrica) and ridge gourd (Luffa acutangula). · Scientific reports
- 4.PMID: 35059295 (2022) — Streptococcus pyogenes secondary impetigo due to loofah sponge use. · IDCases
- 5.PMID: 35180468 (2022) — An in vitro evaluation of luffa cylindrica stem sap in preadipocytes and dermal fibroblasts.