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Silphium perfoliatum
This herb is NOT recommended during pregnancy due to potential risks to the developing fetus.
This herb is NOT recommended while breastfeeding as effects on infants are unknown.
Consult your healthcare provider before use.
Large North American prairie herb used by Native Americans as medicine for fever, rheumatism, and liver support.
Large North American prairie herb used by Native Americans as medicine for fever, rheumatism, and liver support. Key active compounds include resin, sesquiterpene lactones, flavonoids.
resin, along with sesquiterpene lactones and flavonoids, are the primary bioactive compounds in Silphium perfoliatum. These compounds modulates NF-κB and COX-2 inflammatory pathways, stimulates digestive enzyme secretion and GI motility.
Anti-inflammatory
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Digestive tonic
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Fever management
Fever
Based on traditional use; clinical evidence limited
Rheumatism
Based on traditional use; clinical evidence limited
Liver complaints
Based on traditional use; clinical evidence limited
Indigestion
Based on traditional use; clinical evidence limited
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