PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
A combination extract of Smilax china, Hemidesmus indicus, and Nigella Sativa was reported to completely cure cases of oral cancer [PMID:22557660]
Root extracts and nanovesicles demonstrated anti-proliferative and pro-apoptotic effects in HepG2 cells [PMID:35991850, PMID:41529459]
Pectic polysaccharides and other isolated polysaccharides improved symptoms and reduced inflammatory mediators in DSS-induced mouse models [PMID:37107427, PMID:34893269]
Extracts reduced serum uric acid levels and improved renal function by inhibiting xanthine oxidase activity in chicken models [PMID:38861845]
Astilbin significantly alleviated LPS-induced endometritis in rats [PMID:40274031]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 32905089 (2020) — Influence of phytochemicals in induced psoriasis (Review). · Experimental and therapeutic medicine
- 2.PMID: 40383248 (2025) — Smilax china L. Rhizome extract enhances anti-tumor immune responses by resetting M2-like macrophages and tumor-associated macrophages to M1-like via ERK1/2 signaling. · Journal of ethnopharmacology
- 3.PMID: 37541403 (2024) — Smilax china L.: A review of its botany, ethnopharmacology, phytochemistry, pharmacological activities, actual and potential applications. · Journal of ethnopharmacology
- 4.PMID: 35677108 (2022) — Diosgenin: An Updated Pharmacological Review and Therapeutic Perspectives. · Oxidative medicine and cellular longevity
- 5.PMID: 22557660 (1989)