PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Active compounds
Mechanism of action
Clinical evidence
Oral administration of Melon GliSODin (500.4 mg/day) tended to be associated with a larger improvement in subjective symptoms and motor function in women aged 50-80 years [PMID:35628874]
Supplementation with GliSODin was effective in controlling the thickness of the carotid artery intima and media layers in active adults with cardiovascular risk factors [PMID:17441415]
In international level rowers, 6-week supplementation with GliSODin resulted in significantly lower levels of creatine kinase (CK) and interleukin-6 (IL-6) [PMID:36290341]
In a mouse model, Melon GliSODin suppressed liver fibrosis and fat accumulation by reducing fat synthesis and activating antioxidative mechanisms [PMID:31374969]
In rats, GliSODin demonstrated a protective effect against azoxymethane-induced oxidative stress and carcinogenesis in the colon [PMID:34916376]
Dosage & administration
Evidence summary
PubMed sources
- 1.PMID: 34916376 (2021) — Protective role of a melon superoxide dismutase combined with gliadin (GliSODin) on the status of lipid peroxidation and antioxidant defense against azoxymethane-induced experimental colon carcinogenesis. · Journal of cancer research and therapeutics
- 2.PMID: 28825637 (2017) — Superoxide Dismutases in Pancreatic Cancer. · Antioxidants (Basel, Switzerland)
- 3.PMID: 35628874 (2022) — Clinical Efficacy of Melon GliSODin® for the Treatment of Aging-Related Dysfunction in Motor Organs-A Double Blind, Randomized Placebo-Controlled Study. · Journal of clinical medicine
- 4.PMID: 31374969 (2019) — Melon GliSODin® Prevents Diet-Induced NASH Onset by Reducing Fat Synthesis and Improving Liver Function. · Nutrients
- 5.PMID: 15742357 (2004) — Supplementation with gliadin-combined plant superoxide dismutase extract promotes antioxidant defences and protects against oxidative stress.