PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Steroid constituents (specifically compound 10) demonstrated superior anti-inflammatory activity and significant inhibition of NLRP3 inflammasome activation in vitro and in vivo [PMID:40113066].
Isolated clerodane diterpenoids and acetophenones showed anti-neuroinflammatory activity via regulation of NLRP3 and IL-1β [PMID:42090826].
Evidence summary
PubMed sources
- 1.PMID: 36501274 (2022) — Allelopathy and Allelochemicals of Solidago canadensis L. and S. altissima L. for Their Naturalization. · Plants (Basel, Switzerland)
- 2.PMID: 36903973 (2023) — Cytogeography of Naturalized Solidago canadensis Populations in Europe. · Plants (Basel, Switzerland)
- 3.PMID: 36056470 (2022) — Selected Aspects of Invasive Solidago canadensis with an Emphasis on Its Allelopathic Abilities: A Review. · Chemistry & biodiversity
- 4.PMID: 38999585 (2024) — The Invasive Alien Plant Solidago canadensis: Phytochemical Composition, Ecosystem Service Potential, and Application in Bioeconomy. · Plants (Basel, Switzerland)
- 5.PMID: 40113066 (2025) — Steroid constituents of Solidago canadensis alleviate LPS-induced inflammation via AMPK regulated mitophagy/NLRP3 and NF-κB pathway.