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Spigelia marilandica
This herb is NOT recommended during pregnancy due to potential risks to the developing fetus.
This herb is NOT recommended while breastfeeding as effects on infants are unknown.
Consult your healthcare provider before use.
North American native herb used by Native Americans and Eclectic physicians for intestinal worms and cardiac conditions.
North American native herb used by Native Americans and Eclectic physicians for intestinal worms and cardiac conditions. Key active compounds include spigeline, alkaloids, resin.
spigeline, along with alkaloids and resin, are the primary bioactive compounds in Spigelia. The specific pharmacological pathways require further study, though traditional use supports its efficacy.
Antiparasitic
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Anthelmintic
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Cardiac tonic (historical)
Cherokee anthelmintic
Based on traditional use; clinical evidence limited
Eclectic worm remedy
Based on traditional use; clinical evidence limited
Cardiac herb
Based on traditional use; clinical evidence limited
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