This product is not intended to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the Food and Drug Administration.
Acmella caulirhiza
This herb is NOT recommended during pregnancy due to potential risks to the developing fetus.
This herb is NOT recommended while breastfeeding as effects on infants are unknown.
Consult your healthcare provider before use.
African species of the toothache plant used across sub-Saharan Africa for toothache, immune support, and as a general antimicrobial.
African species of the toothache plant used across sub-Saharan Africa for toothache, immune support, and as a general antimicrobial. Key active compounds include spilanthol, N-isobutylamides, flavonoids.
spilanthol, along with N-isobutylamides and flavonoids, are the primary bioactive compounds in Spilanthes African. These compounds modulates NF-κB and COX-2 inflammatory pathways, disrupts microbial cell membranes and inhibits pathogen growth, modulates immune cell activity and cytokine production.
Local anesthetic
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Immune stimulant
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Antimicrobial
Anti-inflammatory
Toothache treatment
Based on traditional use; clinical evidence limited
Antimicrobial infections
Based on traditional use; clinical evidence limited
Traditional African medicine
Based on traditional use; clinical evidence limited
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